Article
Detecting low-quality markers using map expanders.
Genetic epidemiology - 1 Nov 2003
Ekstrøm Claus Thorn
Abstract excerpt
Genetic marker data play a crucial role in gene mapping, and genotyping errors may have substantial influence on the power to detect and the precision to locate disease loci. Statistical methods can identify individuals, markers, or pedigrees with a high likelihood of containing genotyping errors, and the putative erroneous genotypes can then be rechecked and either verified, removed, or corrected to reduce the...
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