Article
Method for constructing confidently ordered linkage maps.
Genetic epidemiology - 1 Jan 1999
Broman K W, Weber J L
Abstract excerpt
We describe a method for identifying, from a comprehensive genetic map, the most dense framework of confidently ordered markers. The approach uses the number of observed recombination events between each pair of markers, and finds the largest subset of markers for which adjacent loci are separated by at least one recombination. We illustrate the approach using a short region of chromosome 7p.
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