Article
glial cells missing: a binary switch between neuronal and glial determination in Drosophila.
Cell - 22 Sept 1995
Hosoya T, Takizawa K, Nitta K, Hotta Y
Abstract excerpt
In the Drosophila CNS, both neurons and glial are derived from neuroblasts. We have identified a gene, glial cells missing (gcm), that encodes a novel nuclear protein expressed transiently in early glial cells. Its mutation causes presumptive glial cells to differentiate into neurons, whereas its...
Topics
- Amino Acid Sequence
- Animals
- Cell Differentiation
- Cell Movement
- Central Nervous System
- Drosophila
- Gene Expression Regulation, Developmental
- Genes, Insect
- Molecular Sequence Data
- Mutation
- Neuroglia
- Neurons
- Nuclear Proteins
- Peripheral Nervous System