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Article

Synaptotagmin 7 splice variants differentially regulate synaptic vesicle recycling.

The EMBO journal - 15 Oct 2003

Virmani Tuhin, Han Weiping, Liu Xinran, Südhof Thomas C, Kavalali Ege T

Abstract excerpt

The speed of synaptic vesicle recycling determines the efficacy of neurotransmission during repetitive stimulation. Synaptotagmins are synaptic C(2)-domain proteins that are involved in exocytosis, but have also been linked to endocytosis. We now demonstrate that upon expression in transfected neurons, a short splice variant of synaptotagmin 7 that lacks C(2)-domains accelerates endocytic recycling of synaptic...

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Identifiers

PMID: 14532108
DOI: 10.1093/emboj/cdg514
PMCID: PMC213769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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