Article
Detection of regulatory circuits by integrating the cellular networks of protein-protein interactions and transcription regulation.
Nucleic acids research - 15 Oct 2003
Yeger-Lotem Esti, Margalit Hanah
Abstract excerpt
The post-genomic era is marked by huge amounts of data generated by large-scale functional genomic and proteomic experiments. A major challenge is to integrate the various types of genome-scale information in order to reveal the intra- and inter- relationships between genes and proteins that constitute a living cell. Here we present a novel application of classical graph algorithms to integrate the cellular...
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