Article

The transcription factor basal regulatory network of Homo sapiens and Saccharomyces cerevisiae: uncovering the relationship between topology and phenotype

2019-06-12

Abstract excerpt

Transcription factors play a key role in controlling which proteins are made by a cell. As transcription factors are themselves proteins, they are part of a complex interconnected and self-regulated network. We define the transcription factor basal regulatory network (TFBRN) as the network formed by the interactions between transcription factors (TFs) as proteins acting on target genes which are themselves TFs. Th...

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Literature Corpus work: 05b2d9c1-b03b-569a-b8de-261c33ecdd6e
DOI: 10.1101/669697

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