Article
An interaction domain in Slob necessary for its binding to the slowpoke calcium-dependent potassium channel.
Neuropharmacology - 1 Nov 2003
Zhou Yi, Fei Hong, Levitan Irwin B
Abstract excerpt
Slob modulates the activity of the Drosophila Slowpoke calcium-dependent potassium channel (dSlo) via its direct binding to the channel. To characterize the molecular detail of the protein-protein interaction between Slob and dSlo, we constructed a series of Slob mutants that are progressively truncated at either the carboxyl or amino terminal end, and examined the binding of these Slob mutants to dSlo using a...
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