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Article

CTLA4 polymorphism in Spanish patients with systemic lupus erythematosus.

Human immunology - 1 Oct 2003

Aguilar Francisco, Torres Belén, Sánchez-Román Julio, Núñez-Roldán Antonio, González-Escribano María Francisca

Abstract excerpt

The cytotoxic T-lymphocyte antigen 4 (CTLA4, CD152) gene is a positional and functional candidate gene to susceptibility to systemic lupus erythematosus (SLE) because CTLA4 gene maps in the described SLE risk region 2q33 and CTLA4 molecule has an inhibitory effect on T-cell activation. Several polymorphisms have been described in CTLA4 gene, among them, a T/C change at position -1722, a C/T transition at position...

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Source

Identifiers

PMID: 14522090
DOI: 10.1016/s0198-8859(03)00171-x

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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