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CTLA-4 -1722T/C polymorphism and systemic lupus erythematosus susceptibility: a meta-analysis involving ten separate studies.

Immunological investigations - 1 Jan 2013

Zhu Ji-Min, Li Bai-Kun, Chen Gui-Mei, Feng Chen-Chen, Cen Han, Fan Yin-Guang, Wang Bin, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) -1722T/C polymorphism has been identified as a susceptibile gene for systemic lupus erythematosus (SLE), but studies are inconsistent. To better assess the association between CTLA-4 -1722T/C polymorphism and SLE, a meta-analysis was performed, including 10 studies, total of 1 387 patients and 1 617 controls. Overall, the CTLA-4 -1722T/C polymorphism was...

Topics

Asian People
CTLA-4 Antigen
Female
Genetic Predisposition to Disease
Genotype
Humans
Lupus Erythematosus, Systemic
Male
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23323522
DOI: 10.3109/08820139.2012.724752

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