Article
CTLA-4 gene polymorphism and the risk of systemic lupus erythematosus in the Chinese population.
Journal of biomedicine & biotechnology - 1 Jan 2011
Taha Khalaf Ahmad, Song Ji-Quan, Gao Ting-Ting, Yu Xiang-Ping, Lei Tie-Chi
Abstract excerpt
Several variants of CTLA-4 have been reported to be associated with susceptibility systemic lupus erythematosus (SLE); however, findings have been inconsistent across different populations. Using a case-control study design, we have investigated the role of CTLA-4 polymorphism at positions -1661 and -1722 on SLE susceptibility in our Chinese SLE population in central China's Hubei province. Samples were collected...
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