FXa-induced intracellular signaling links coagulation to neoangiogenesis: potential implications for fibrosis.

Abstract excerpt

Fibrosis represents the end-stage of a broad range of disorders affecting organ function. These disorders are often associated with aberrant angiogenesis, but whether vascular abnormalities during fibrosis are characterized by excessive or diminished neo-vascularization remains questionable. Strikingly, activation of the coagulation cascade is frequently observed in association with the progression of...

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