Article
Multiple quantitative trait loci modify the heart failure phenotype in murine cardiomyopathy.
Human molecular genetics - 1 Dec 2003
Le Corvoisier Philippe, Park Hyun-Young, Carlson Kerri M, Marchuk Douglas A, Rockman Howard A
Abstract excerpt
The variability in outcome of heart failure patients depends on a number of factors including differences in their genetic background. To identify novel genes that modify the human heart failure phenotype, we used a strategy of quantitative trait locus (QTL) mapping in an experimental mouse model...
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