Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients.

Journal of clinical pharmacology - 1 Oct 2003

Mai Ingrid, Störmer Elke, Goldammer Mark, Johne Andreas, Krüger Hagen, Budde Klemens, Roots Ivar

Abstract excerpt

This retrospective study investigated the impact of MDR1 haplotypes derived from the single-nucleotide polymorphisms (SNPs) 2677G>T (exon 21) and 3435C>T (exon 26) on the pharmacokinetics of cyclosporine in 98 renal transplant patients. Based on SNPs 2677 and 3435, four different haplotypes and n...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Area Under Curve
Share to Cyclosporine
Share to Genes, MDR

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germany

Share to Kidney Transplantation

Share to Time Factors

Share to Treatment Outcome

Share to White People

Source

Identifiers

PMID: 14517192
DOI: 10.1177/0091270003257222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14517192-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MDR1 haplotypes do not affect the steady-state pharmacokinetics of cyclosporine in renal transplant patients.PMID 14517192Read ↗

MDR1 haplotypes derived from exons 21 and 26 do not affect the steady-state pharmacokinetics of tacrolimus in renal transplant patients.Semantic proximity Read ↗

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene.Semantic proximity Read ↗

Impact of MDR1 haplotypes derived from C1236T, G2677T/A and C3435T on the pharmacokinetics of single-dose oral digoxin in healthy Chinese volunteers.Semantic proximity Read ↗

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients.Semantic proximity Read ↗

C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects.Semantic proximity Read ↗

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantationSemantic proximity Read ↗

Multidrug-resistance 1 gene single-nucleotide polymorphisms do not influence long-term graft survival after kidney transplantation.Semantic proximity Read ↗

MDR1 C3435T polymorphisms correlate with cyclosporine levels in de novo renal recipients.Semantic proximity Read ↗

Multidrug resistance gene-1 (MDR-1) haplotypes have a minor influence on tacrolimus dose requirements.Semantic proximity Read ↗

ATP-binding cassette subfamily B member 1 polymorphisms do not determine cyclosporin exposure, acute rejection or nephrotoxicity after heart transplantation.Semantic proximity Read ↗

Effect of MDR1 C1236T polymorphism on cyclosporine pharmacokinetics: A systematic review and meta-analysis.Semantic proximity Read ↗

Meta-analysis of the effect of MDR1 C3435T polymorphism on cyclosporine pharmacokinetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.