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The Adenomatous Polyposis Coli (APC) gene microsatellite marker D5S1385 is equally informative for loss of heterozygosity as the marker D5S346.

Experimental and molecular pathology - 1 Oct 2003

Zauber N Peter, Sabbath-Solitare Marlene, Marotta Stephen P, Bishop D Timothy

Abstract excerpt

Molecular analyses for loss of heterozygosity (LOH) at a gene locus are used to identify genomic imbalance in tumor tissue. A frequently utilized microsatellite marker for the Adenomatous Polyposis Coli (APC) gene is denoted D5S346. However, when an individual has two identical forms of this microsatellite, then a second microsatellite, also near the APC gene, is needed. We present data on an APC microsatellite...

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Source

Identifiers

PMID: 14516776
DOI: 10.1016/s0014-4800(03)00069-8

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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