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Article

Respiratory survival mechanisms in acetylcholinesterase knockout mouse.

The European journal of neuroscience - 1 Sept 2003

Chatonnet Fabrice, Boudinot Eliane, Chatonnet Arnaud, Taysse Laurent, Daulon Sébastien, Champagnat Jean, Foutz Arthur S

Abstract excerpt

Cholinergic neurotransmission ensures muscle contraction and plays a role in the regulation of respiratory pattern in the brainstem. Inactivation of acetylcholinesterase (AChE) by organophosphates produces respiratory failure but AChE knockout mice survive to adulthood. Respiratory adaptation mec...

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Identifiers

PMID: 14511322
DOI: 10.1046/j.1460-9568.2003.02867.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14511322-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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