Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chronic acetylcholinesterase overexpression induces multilevelled aberrations in mouse neuromuscular physiology.

The Journal of physiology - 1 Jan 2003

Farchi Noa, Soreq Hermona, Hochner Binyamin

Abstract excerpt

Chronic overexpression of the acetylcholine-hydrolysing enzyme acetylcholinesterase (AChE) is a notable consequence of exposure to anticholinesterase drugs or poisons. However, the physiological consequences for the resultant neuromuscular disfunction have not yet been carefully analysed. Here we report detailed dissection of the different components of neuromuscular function in transgenic mice previously shown...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholinesterase
Share to Diaphragm
Share to Electric Stimulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Vitro Techniques

Share to Mice, Inbred Strains

Share to Neuromuscular Junction

Share to Synapses

Share to Synaptic Transmission

Source

Open in PubMed Open full text

Identifiers

PMID: 12509486
DOI: 10.1113/jphysiol.2002.030841
PMCID: PMC2342479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chronic acetylcholinesterase overexpression induces multilevelled aberrations in mouse neuromuscular physiology.PMID 12509486Read ↗

Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.Semantic proximity Read ↗

Synaptogenesis and myopathy under acetylcholinesterase overexpression.Semantic proximity Read ↗

Striking denervation of neuromuscular junctions without lumbar motoneuron loss in geriatric mouse muscle.Semantic proximity Read ↗

Ultrastructure of neuromuscular junctions in Drosophila: comparison of wild type and mutants with increased excitability.Semantic proximity Read ↗

Function of neuromuscular synapses in the zebrafish choline-acetyltransferase mutant bajan.Semantic proximity Read ↗

Post-synaptic morphology of mouse neuromuscular junctions is linked to muscle fibre typeSemantic proximity Read ↗

Chronic striatal cholinergic interneuron excitation induces clinically-relevant dystonic behavior in miceSemantic proximity Read ↗

A transgenic mouse model of the slow-channel syndrome.Semantic proximity Read ↗

Early and Selective Loss of Neuromuscular Synapse Subtypes with Low Sprouting Competence in Motoneuron DiseasesSemantic proximity Read ↗

Active calcium accumulation underlies severe weakness in a panel of mice with slow-channel syndrome.Semantic proximity Read ↗

Rescue of the acetylcholinesterase knockout mouse by feeding a liquid diet; phenotype of the adult acetylcholinesterase deficient mouse.Semantic proximity Read ↗

Cholinergic Transmission in an Inducible Transgenic Mouse Model of Paroxysmal DystoniaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.