Article
Lack of apoptosis in PanIN-1 and PanIN-2 lesions associated with pancreatic ductal adenocarcinoma is not dependent on K-ras status.
Pancreas - 1 Oct 2003
Lüttges Jutta, Neumann Svenja, Jesenofsky Ralf, Jesnowski Ralf, Borries Vivian, Löhr Matthias, Klöppel Günter
Abstract excerpt
INTRODUCTION: K-ras mutations are present in most ductal adenocarcinomas (DACs) of the pancreas and may also be found in ductal precursor lesions and even in normal ductal epithelium. The question is addressed whether mutated K-ras interferes with the regulation of apoptosis or proliferation. MET...
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