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Article

Stat3 and NF-kappaB activation prevents apoptosis in pancreatic carcinogenesis.

Gastroenterology - 1 Dec 2002

Greten Florian R, Weber Christoph K, Greten Tim F, Schneider Günter, Wagner Martin, Adler Guido, Schmid Roland M

Abstract excerpt

BACKGROUND & AIMS: Human pancreatic adenocarcinoma has an overall poor prognosis. Therapeutic efforts are often ineffective because of late diagnosis and a high degree of chemoresistance. Overexpression of transforming growth factor alpha in the pancreas of transgenic mice causes the formation of premalignant ductal lesions and the development of invasive ductal adenocarcinoma. The aim of the present study was to...

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Source

Identifiers

PMID: 12454861
DOI: 10.1053/gast.2002.37075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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