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Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer

14 Jun 2006

Abstract excerpt

AIM: To determine the role of two antiapoptotic proteins of the inhibitor of apoptosis protein family, cellular inhibitor of apoptosis protein 1 (cIAP1) and cellular inhibitor of apoptosis protein 2 (cIAP2), in human pancreatic carcinogenesis. METHODS: mRNA levels were measured in pancreatic tissues and pancreatic cancer cell lines by quantitative reverse transcriptase PCR. Protein expression was assessed in...

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PMID: 16775116
DOI: 10.1136/jcp.2006.038257

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