Article
Mitochondrial aldehyde dehydrogenase polymorphism in Asian and American Indian populations: detection of new ALDH2 alleles.
Alcoholism, clinical and experimental research - 1 Oct 1995
Novoradovsky A, Tsai S J, Goldfarb L, Peterson R, Long J C, Goldman D
Abstract excerpt
Genetic deficiency of the mitochondrial aldehyde dehydrogenase (ALDH2) is frequent in Asian peoples where it is an important factor negatively regulating drinking behavior. To obtain additional information on gene geography of known ALDH2 alleles, and look for new variants, ALDH2 genes were evalu...
Topics
- Alcoholism
- Aldehyde Dehydrogenase
- Alleles
- Asian People
- Base Composition
- DNA
- Gene Frequency
- Humans
- Indians, North American
- Isoenzymes
- Mitochondria, Liver
- Molecular Sequence Data
- Polymorphism, Genetic
- Reference Values
- Taiwan
- United States