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Article

Clinical significance of CCR4 expression in adult T-cell leukemia/lymphoma: its close association with skin involvement and unfavorable outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2003

Ishida Takashi, Utsunomiya Atae, Iida Shinsuke, Inagaki Hiroshi, Takatsuka Yoshifusa, Kusumoto Shigeru, Takeuchi Genji, Shimizu Shigeki, Ito Masato, Komatsu Hirokazu, Wakita Atsushi, Eimoto Tadaaki, Matsushima Kouji, Ueda Ryuzo

Abstract excerpt

Adult T-cell leukemia/lymphoma (ATLL) is a distinct clinical entity among mature T-cell neoplasms, and its causative agent has been confirmed to be long-term infection by human T-lymphotropic virus type 1. A recent study demonstrated frequent expression of a chemokine receptor, CC chemokine receptor (CCR)4, which is known as a Th2 marker but not CXC chemokine receptor (CXCR)3, which is known as a Th1 marker,...

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Share to Chemokines, CC
Share to Leukemia, T-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymph Nodes

Share to Lymphoma, T-Cell

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Share to Receptors, Chemokine

Share to Receptors, CXCR3

Source

Identifiers

PMID: 14506150

Genes

CCR4
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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