Article
Cutaneous anaplastic large cell lymphoma and peripheral T-cell lymphoma NOS show distinct chromosomal alterations and differential expression of chemokine receptors and apoptosis regulators.
The Journal of investigative dermatology - 1 Feb 2010
van Kester Marloes S, Tensen Cornelis P, Vermeer Maarten H, Dijkman Remco, Mulder Aat A, Szuhai Karoly, Willemze Rein, van Doorn Remco
Abstract excerpt
Primary cutaneous anaplastic large cell lymphoma (C-ALCL) has an indolent clinical course and favorable prognosis. On the contrary, primary cutaneous peripheral T-cell lymphoma not otherwise specified (PTL-NOS) shows aggressive clinical behavior. To identify genomic events relevant in the pathogenesis of these cutaneous T-cell lymphomas (CTCLs), we carried out array-based comparative genomic hybridization (CGH)...
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