Article
Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor.
Experimental cell research - 1 Oct 2003
Peace Belinda E, Hill Kara J, Degen Sandra J F, Waltz Susan E
Abstract excerpt
Heterogeneous receptor-receptor interactions may play a role in intracellular signaling. Accordingly, the interaction of two dissimilar tyrosine kinase receptors, Ron and epidermal growth factor receptor (EGFR) was investigated. The functional interaction of Ron and EGFR in cell scatter and oncogenic transformation was investigated in vivo. Transfection of a dominant negative form of EGFR into human embryonic...
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