Qualitative defects in natural killer cell function in ia osteopetrotic rats.

doi:10.1002/jbmr.5650070811

Article

Qualitative defects in natural killer cell function in ia osteopetrotic rats.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 1992

Schneider G B, Relfson M, Ellis T M

Abstract excerpt

Recent studies have provided evidence that cells of the immune system and their associated cytokines function in the regulation of bone turnover. The incisors absent (ia) osteopetrotic rat represents a model in which a defect in the immune system and bone resorption can be studied. Osteopetrosis...

Topics

Animals
Cytotoxicity, Immunologic
Disease Models, Animal
Indomethacin
Interleukin-2
Killer Cells, Natural
Leukocyte Count
Mutation
Osteopetrosis
Phenotype
Rats
Rats, Mutant Strains

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