Article
Natural killer cell biology illuminated by primary immunodeficiency syndromes in humans.
Clinical immunology (Orlando, Fla.) - 1 Apr 2017
Voss Matthias, Bryceson Yenan T
Abstract excerpt
Natural killer (NK) cells are innate immune cytotoxic effector cells well known for their role in antiviral immunity and tumor immunosurveillance. In parts, this knowledge stems from rare inherited immunodeficiency disorders in humans that abrogate NK cell function leading to immune impairments, most notably associated with a high susceptibility to viral infections. Phenotypically, these disorders range from...
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