Article
A comparative study of resistance to MHV3 infection in genetically homogeneous and heterogeneous mouse populations.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jan 1992
Damy S B, Vassão R C, Lucchiari M A, Pereira C A, Sant'Anna O A
Abstract excerpt
Resistance to MHV3 infection was investigated in genetically homogeneous inbred (A/J, BALB/c) and genetically selected (High, Low) mouse lines. The A/J and L lines are resistant and the BALB/c and H mice are susceptible. The genetic analysis was performed on the F1 hybrids, as well as on the genetically heterogeneous F2 populations and backcrosses bred from HxL and A/JxBALB/c lines. The mortality rates of the F1...
Topics
- Animals
- Coronavirus Infections
- Crosses, Genetic
- Female
- Genetic Predisposition to Disease
- Hepatitis, Viral, Animal
- Immunity, Innate
- Male
- Mice
- Mice, Inbred A