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Article

Association of HLA phenotype with response to active specific immunotherapy of melanoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jul 1992

Mitchell M S, Harel W, Groshen S

Abstract excerpt

PURPOSE: Only a proportion of patients with disseminated melanoma who were immunized successfully with a therapeutic melanoma vaccine (theraccine) had a major clinical response. We investigated whether there was a correlation between their HLA phenotypes and the likelihood of a clinical response. PATIENTS AND METHODS: Seventy patients with disseminated melanoma who were treated with melanoma theraccine were...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Female
Genes, MHC Class I
Humans
Immunotherapy, Active
Lymphocytes
Male
Melanoma
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Treatment Outcome

Tumor Cells, Cultured

Source

Identifiers

PMID: 1607920
DOI: 10.1200/JCO.1992.10.7.1158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1607920-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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