Article
The SA gene: predisposition to hypertension and renal function in man.
Clinical science (London, England : 1979) - 1 Jun 1995
Harrap S B, Samani N J, Lodwick D, Connor J M, Fraser R, Davies D L, Lever A F, Foy C J, Watt G C
Abstract excerpt
1. The SA gene is expressed in the kidneys and is associated with hypertension in man and experimental animal models. Predisposition to hypertension is associated with renal haemodynamic abnormalities and increased renal SA gene expression. 2. We studied the distribution of the SA gene alleles (A1, A2), defined by the PstI polymorphism, in young adults with contrasting predisposition to hypertension to determine...
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