Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae.

The Journal of cell biology - 1 Oct 1992

Sullivan D S, Huffaker T C

Abstract excerpt

tub2-401 is a cold-sensitive allele of TUB2, the sole gene encoding beta-tubulin in the yeast, Saccharomyces cerevisiae. At 18 degrees C, tub2-401 cells are able to assemble spindle microtubules but lack astral microtubules. Under these conditions, movement of the spindle to the bud neck is blocked. However, spindle elongation and chromosome separation are unimpeded and occur entirely within the mother cell....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cell Nucleus
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microtubules

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Spindle Apparatus

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 1400581
DOI: 10.1083/jcb.119.2.379
PMCID: PMC2289657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae.PMID 1400581Read ↗

Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae.Semantic proximity Read ↗

The V260I mutation in fission yeast alpha-tubulin Atb2 affects microtubule dynamics and EB1-Mal3 localization and activates the Bub1 branch of the spindle checkpoint.Semantic proximity Read ↗

An alpha-tubulin mutant demonstrates distinguishable functions among the spindle assembly checkpoint genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

STU1, a suppressor of a beta-tubulin mutation, encodes a novel and essential component of the yeast mitotic spindle.Semantic proximity Read ↗

Single site alpha-tubulin mutation affects astral microtubules and nuclear positioning during anaphase in Saccharomyces cerevisiae: possible role for palmitoylation of alpha-tubulin.Semantic proximity Read ↗

Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes.Semantic proximity Read ↗

Suppression of a conditional mutation in alpha-tubulin by overexpression of two checkpoint genes.Semantic proximity Read ↗

Consequences of defective tubulin folding on heterodimer levels, mitosis and spindle morphology in Saccharomyces cerevisiae.Semantic proximity Read ↗

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells.Semantic proximity Read ↗

Analysis of Tub4p, a yeast gamma-tubulin-like protein: implications for microtubule-organizing center function.Semantic proximity Read ↗

Dynamic positioning of mitotic spindles in yeast: role of microtubule motors and cortical determinants.Semantic proximity Read ↗

Identification of novel temperature-sensitive lethal alleles in essential beta-tubulin and nonessential alpha 2-tubulin genes as fission yeast polarity mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.