Article
Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae.
The Journal of cell biology - 1 Oct 1992
Sullivan D S, Huffaker T C
Abstract excerpt
tub2-401 is a cold-sensitive allele of TUB2, the sole gene encoding beta-tubulin in the yeast, Saccharomyces cerevisiae. At 18 degrees C, tub2-401 cells are able to assemble spindle microtubules but lack astral microtubules. Under these conditions, movement of the spindle to the bud neck is blocked. However, spindle elongation and chromosome separation are unimpeded and occur entirely within the mother cell....
Topics
- Anaphase
- Cell Division
- Cell Nucleus
- DNA Replication
- Microtubules
- Mutation
- Saccharomyces cerevisiae
- Spindle Apparatus
- Tubulin