Article
Dynamic positioning of mitotic spindles in yeast: role of microtubule motors and cortical determinants.
Molecular biology of the cell - 1 Nov 2000
Yeh E, Yang C, Chin E, Maddox P, Salmon E D, Lew D J, Bloom K
Abstract excerpt
In the budding yeast Saccharomyces cerevisiae, movement of the mitotic spindle to a predetermined cleavage plane at the bud neck is essential for partitioning chromosomes into the mother and daughter cells. Astral microtubule dynamics are critical to the mechanism that ensures nuclear migration to the bud neck. The nucleus moves in the opposite direction of astral microtubule growth in the mother cell, apparently...
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