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Article

p53 mutations in formaldehyde-induced nasal squamous cell carcinomas in rats.

Cancer research - 1 Nov 1992

Recio L, Sisk S, Pluta L, Bermudez E, Gross E A, Chen Z, Morgan K, Walker C

Abstract excerpt

Formaldehyde induces squamous cell carcinomas in the nasal passages of rats following chronic inhalation exposure at concentrations of > or = 10 ppm. We have examined the complementary DNA of the tumor suppressor gene p53 from 11 primary formaldehyde-induced tumors for mutation using DNA sequence analysis. A polymerase chain reaction-amplified fragment of the rat p53 complementary DNA containing the...

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Identifiers

PMID: 1394239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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