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Article

Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.

Biochemical and biophysical research communications - 15 Jun 1995

Hamby C V, Mendola C E, Potla L, Stafford G, Backer J M

Abstract excerpt

The putative metastasis suppressor genes, NME1(nm23-1) and NME2(nm23-2), were examined in a model system we developed to approximate the dissemination of melanoma from a primary skin tumor. We utilized two autologous human melanoma cell lines, IV Cl 1 and IV Cl 3, which displayed qualitatively different metastatic phenotypes following subdermal inoculation into nude mice. Highly metastatic IV Cl 1 cells expressed...

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Identifiers

PMID: 7794272
DOI: 10.1006/bbrc.1995.1852

Genes

NME1
NME2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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