Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.

doi:10.1006/bbrc.1995.1852

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.

Biochemical and biophysical research communications - 15 Jun 1995

Hamby C V, Mendola C E, Potla L, Stafford G, Backer J M

Abstract excerpt

The putative metastasis suppressor genes, NME1(nm23-1) and NME2(nm23-2), were examined in a model system we developed to approximate the dissemination of melanoma from a primary skin tumor. We utilized two autologous human melanoma cell lines, IV Cl 1 and IV Cl 3, which displayed qualitatively di...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cell Line
Clone Cells
DNA Primers
Gene Expression
Genes, Tumor Suppressor
Glycine
Humans
Melanoma
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Molecular Sequence Data

Monomeric GTP-Binding Proteins

NM23 Nucleoside Diphosphate Kinases

Neoplasm Metastasis

Neuroblastoma

Source

Open in PubMed

Identifiers

PMID: 7794272
DOI: 10.1006/bbrc.1995.1852

Genes

NME1
NME2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7794272-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.PMID 7794272Read ↗

Expression ofnma, a novel gene, inversely correlates with the metastatic potential of human melanoma cell lines and xenograftsSemantic proximity Read ↗

Metastasis suppressor <scp>NME</scp>1 regulates melanoma cell morphology, self‐adhesion and motility via induction of fibronectin expressionSemantic proximity Read ↗

Identification of a gene expression signature associated with the metastasis suppressor function of NME1: prognostic value in human melanomaSemantic proximity Read ↗

Increased expression of the nme1 gene is associated with metastasis in epithelial ovarian cancerSemantic proximity Read ↗

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells.Semantic proximity Read ↗

Genetic polymorphisms of metastasis suppressor gene NME1 and breast cancer survival.Semantic proximity Read ↗

The metastatic microenvironment: Claudin-1 suppresses the malignant phenotype of melanoma brain metastasis.Semantic proximity Read ↗

TM7XN1, a novel human EGF‐TM7‐like cDNA, detected with mRNA differential display using human melanoma cell lines with different metastatic potential1Semantic proximity Read ↗

Expression of <i>MAGE</i> genes in primary and metastatic cutaneous melanomaSemantic proximity Read ↗

Metastatic potential of human melanoma cells in nude mice--characterisation of phenotype, cytokine secretion and tumour-associated antigens.Semantic proximity Read ↗

Identification of metastasis-associated genes by transcriptional profiling of a metastasizing versus a non-metastasizing human melanoma cell line.Semantic proximity Read ↗

Establishment of a human melanoma cell line lacking p53 expression and spontaneously metastasizing in nude mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.