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Article

Expression of vacuolar H(+)-ATPase in mouse osteoclasts during in vitro differentiation.

The American journal of physiology - 1 Aug 1992

Wang Z Q, Hemken P, Menton D, Gluck S

Abstract excerpt

Osteoclasts express high levels of a vacuolar H(+)-adenosinetriphosphatase (H(+)-ATPase) on the ruffled membrane which they employ to dissolve bone mineral by acidifying their site of attachment on bone. The factors that control amplification of H(+)-ATPase during osteoclast differentiation are poorly understood. We examined the expression of vacuolar H(+)-ATPase in a cell culture system in which mouse spleen...

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Identifiers

PMID: 1387291
DOI: 10.1152/ajprenal.1992.263.2.F277

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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