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Article

Murine osteoclasts and spleen cell polykaryons are distinguished by mRNA phenotyping.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Apr 1994

Tong H S, Sakai D D, Sims S M, Dixon S J, Yamin M, Goldring S R, Snead M L, Minkin C

Abstract excerpt

To probe osteoclast gene expression, we combined the techniques of cell microisolation and RT-PCR to develop a novel and sensitive method for the isolation and mRNA phenotyping of small numbers of authentic osteoclasts and spleen cell polykaryons. Using this method we report (1) direct evidence for the presence of calcitonin receptor mRNA in osteoclasts, (2) confirmation of the recent finding of osteopontin mRNA...

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PMID: 8030446
DOI: 10.1002/jbmr.5650090418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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