Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

doi:10.1042/bj3030191

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Article

Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

The Biochemical journal - 1 Oct 1994

van Hille B, Richener H, Schmid P, Puettner I, Green J R, Bilbe G

Abstract excerpt

The catalytic domain of the vacuolar proton ATPase is composed of a hexamer of three A subunits and three B subunits. Here we describe the cloning and characterization of a cDNA isoform of subunit B, HO57, from an osteoclastoma cDNA library. HO57 is represented by three species of mRNA of 1.6, 2.6 and 2.8 kb and is expressed at low levels in a range of human tissues, but at significantly higher levels in brain,...

Topics

Animals
Base Sequence
Bone Neoplasms
Bone and Bones
Brain
DNA Primers
DNA, Complementary
Embryo, Mammalian
Genetic Variation
Giant Cell Tumor of Bone
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

In Situ Hybridization

Isoenzymes

Kidney

Macromolecular Substances

Mice

Molecular Sequence Data

Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 7945239
DOI: 10.1042/bj3030191
PMCID: PMC1137575

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7945239-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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