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Article

Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

The Biochemical journal - 1 Oct 1994

van Hille B, Richener H, Schmid P, Puettner I, Green J R, Bilbe G

Abstract excerpt

The catalytic domain of the vacuolar proton ATPase is composed of a hexamer of three A subunits and three B subunits. Here we describe the cloning and characterization of a cDNA isoform of subunit B, HO57, from an osteoclastoma cDNA library. HO57 is represented by three species of mRNA of 1.6, 2.6 and 2.8 kb and is expressed at low levels in a range of human tissues, but at significantly higher levels in brain,...

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Identifiers

PMID: 7945239
DOI: 10.1042/bj3030191
PMCID: PMC1137575

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Source receipt: pubmed, retrieved 7 Sept 2026.

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