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Article

Lymphokine-activated killer (LAK) cells discriminate between Epstein-Barr virus (EBV)-positive Burkitt's lymphoma cells.

International journal of cancer - 15 Sept 1990

Misko I S, Schmidt C, Martin N, Moss D J, Sculley T B, Burrows S, Burman K J

Abstract excerpt

We have generated in vitro lymphokine-activated killer (LAK) cells from healthy donors by stimulating their mononuclear leukocytes with recombinant interleukin-2 (rIL-2) (100 U/ml). After 6 days in culture, the lytic properties of the LAK cells were analyzed in the 51Cr-release assay by utilizing a target panel of 6 paired lines consisting of an Epstein-Barr virus (EBV)-positive Burkitt's lymphoma (BL) cell line...

Topics

Animals
Antibodies, Monoclonal
Burkitt Lymphoma
Cell Line
Cytotoxicity, Immunologic
Herpesvirus 4, Human
Humans
Immunologic Surveillance
Interleukin-2
Killer Cells, Lymphokine-Activated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Depletion

Phenotype

Recombinant Proteins

Tumor Cells, Cultured

Tumor Virus Infections

Source

Identifiers

PMID: 2168343
DOI: 10.1002/ijc.2910460312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2168343-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Lymphokine-activated killer (LAK) cells discriminate between Epstein-Barr virus (EBV)-positive Burkitt's lymphoma cells.PMID 2168343Read ↗

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