Article
In vivo Paramecium mutants show that calmodulin orchestrates membrane responses to stimuli.
Cell calcium - 1 Jan 2000
Kung C, Preston R R, Maley M E, Ling K Y, Kanabrocki J A, Seavey B R, Saimi Y
Abstract excerpt
Paramecium generates a Ca2+ action potential and can be considered a one-cell animal. Rises in internal [Ca2+] open membrane channels that specifically pass K+, or Na+. Mutational and patch-clamp studies showed that these channels, like enzymes, are activated by Ca(2+)-calmodulin. Viable CaM muta...
Topics
- Amino Acid Sequence
- Animals
- Calcium
- Calmodulin
- Cell Membrane
- Ion Channels
- Molecular Sequence Data
- Mutation
- Paramecium tetraurelia