Defect of cold-sensitive response in calmodulin mutants of Paramecium and the restoration by cyclic nucleotide.

doi:10.1247/csf.22.493

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Article

Defect of cold-sensitive response in calmodulin mutants of Paramecium and the restoration by cyclic nucleotide.

Cell structure and function - 1 Oct 1997

Kuriu T, Oosawa Y, Watanabe Y, Nakaoka Y

Abstract excerpt

Wild type and calmodulin mutants (cam) of Paramecium tetraurelia were examined for cold-sensitive responses. Among mutants tested, cam12 and cam13 mutants, which have substitutions in N-terminal lobe of calmodulin molecule, reduced both responses in the swimming and the membrane potential. Under...

Topics

Animals
Calmodulin
Cell Movement
Cells, Cultured
Cold Temperature
Cyclic AMP
Cyclic GMP
Membrane Potentials
Mutation
Nucleotides, Cyclic
Paramecium tetraurelia
Patch-Clamp Techniques
Radioimmunoassay
Theophylline
Thermosensing

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