Article
Calmodulin defects cause the loss of Ca2(+)-dependent K+ currents in two pantophobiac mutants of Paramecium tetraurelia.
The Journal of membrane biology - 1 Apr 1990
Preston R R, Wallen-Friedman M A, Saimi Y, Kung C
Abstract excerpt
Two behavioral mutants of Paramecium tetraurelia, pantophobiacs A1 and A2, have single amino acid defects in the structure of calmodulin. The mutants exhibit several major ion current defects under voltage clamp: (i) the Ca2(+)-dependent K+ current activated upon depolarization of Paramecium is g...
Topics
- Amino Acid Sequence
- Animals
- Calcium
- Calmodulin
- Membrane Potentials
- Molecular Sequence Data
- Mutation
- Paramecium
- Potassium
- Potassium Channels
- Sodium
- Sodium Channels