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Article

Hypervariable region diversity of hepatitis C virus and humoral response: comparison between patients with or without cirrhosis.

Journal of medical virology - 1 Sept 1999

Allain J P, Zhai W, Shang D, Timmers E, Alexander G J

Abstract excerpt

To investigate the potential clinical utility of antibody response to HVR1 of HCV, the genomic and amino acid diversity of HVR1 was compared between two groups of four chronic HCV carriers with or without liver cirrhosis. Peptides corresponding to the deduced COOH- and NH2-terminal amino acid sequences of HVR1 were synthesised to assess the reactivity of patient sera to autologous and homologous HVR1 epitopes by...

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Identifiers

PMID: 10440804
DOI: 10.1002/(sici)1096-9071(199909)59:1<25::aid-jmv5>3.0.co;2-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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