Article
The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII.
Genes, chromosomes & cancer - 1 Jan 1992
Varesco L, Caligo M A, Simi P, Black D M, Nardini V, Casarino L, Rocchi M, Ferrara G, Solomon E, Bevilacqua G
Abstract excerpt
The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic cell hybrids and in situ hybridization showed that the gene is located in human chromosome band 17q22. A two-allele...
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