Article
The NM23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII.
Genes, chromosomes & cancer - 1 Jan 1992
Varesco L, Caligo M A, Simi P, Black D M, Nardini V, Casarino L, Rocchi M, Ferrara G, Solomon E, Bevilacqua G
Abstract excerpt
The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process. Recent genetic and immunological data indicate that the NM23-Hl gene encodes a protein with nucleoside diphosphate (NDP) kinase activity. The mapping of NM23-Hl by panels of rodent-human somatic...
Topics
- Alleles
- Animals
- Bacterial Proteins
- Blotting, Southern
- Breast Neoplasms
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Cricetinae
- DNA
- Deoxyribonucleases, Type II Site-Specific
- Genes, Tumor Suppressor
