Article
Chromosomal mapping of the human CNP gene using a meiotic crossover DNA panel, PCR, and allele-specific probes.
Genomics - 1 May 1993
Sprinkle T J, Kouri R E, Fain P D, Stoming T A, Whitney J B
Abstract excerpt
The human 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP) gene is located on chromosome 17, as determined by PCR of somatic cell hybrid DNA panels and confirmed using a mouse-human hybrid containing only human chromosome 17. A polymorphic site (C, T) was previously described at nucleotide 1215 within the most 3' intron of the gene. Nested PCR primer pairs were designed to amplify across this site, and PCR...
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