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Article

The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.

Journal of molecular biology - 25 Aug 1995

Webb P A, Perisic O, Mendola C E, Backer J M, Williams R L

Abstract excerpt

The 2.8 A resolution X-ray structure of NM23-H2 has been determined by molecular replacement using the structure of Myxococcus xanthus nucleoside diphosphate (NDP) kinase. NM23-H2 is a human NDP kinase. The enzyme catalyses phosphoryl transfer, binds DNA, and can activate the transcription of the c-myc oncogene in vitro. NM23 has also been reported to be a suppressor of metastasis in some types of tumours....

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Source

Identifiers

PMID: 7658474
DOI: 10.1006/jmbi.1995.0457

Genes

NDP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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