Treatment of murine CD5- B cells with anti-Ig, but not LPS, induces surface CD5: two B-cell activation pathways.

doi:10.1093/intimm/3.5.467

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Article

Treatment of murine CD5- B cells with anti-Ig, but not LPS, induces surface CD5: two B-cell activation pathways.

International immunology - 1 May 1991

Cong Y Z, Rabin E, Wortis H H

Abstract excerpt

Anti-Ig stimulated murine B cells express high levels of surface CD5 (ly-1) and increased CD44 while maintaining surface IgD, CD23 and J11d. Sorting of CD5- and CD5+ cells demonstrates that anti-Ig induces CD5 expression rather than the selective expansion of CD5+ cells. Anti Ig plus interleukin-6 (IL-6) induces the CD23, IgD, low ly-5 (B220) (CD45low), J11dhigh phenotype of typical CD5+ peritoneal B cells. In...

Topics

Animals
Antibodies, Anti-Idiotypic
Antigens, CD
Antigens, Differentiation
Antigens, Differentiation, B-Lymphocyte
B-Lymphocyte Subsets
CD5 Antigens
Cell Survival
Gene Expression Regulation
Immunoglobulin D
Immunoglobulin M

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunologic Capping

Immunologic Memory

Interleukin-6

Lipopolysaccharides

Lymphocyte Activation

Lymphocyte Cooperation

Mice

Source

Open in PubMed

Identifiers

PMID: 1716972
DOI: 10.1093/intimm/3.5.467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1716972-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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