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Article

Selective activation of Fas/Fas ligand-mediated cytotoxicity by a self peptide.

The Journal of experimental medicine - 1 Jun 1996

Brossart P, Bevan M J

Abstract excerpt

To study how MHC-associated self antigens may regulate the function of T cells in the periphery, we generated CD8+ T cell lines specific for a single residue variant of a self peptide. The self peptide (GAYEFTTL) was isolated from H-2-Kb class I MHC molecules immunopurified from tumor cells. CD8+ CTL lines from H-2b mice were generated against a variant peptide, pE4R, (arginine for glutamic acid at the TCR...

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Identifiers

PMID: 8676065
DOI: 10.1084/jem.183.6.2449
PMCID: PMC2192615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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