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Article

Modification of foot-and-mouth disease virus O1 Caseros after serial passages in the presence of antiviral polyclonal sera.

Journal of virology - 1 Jun 1992

Rojas E R, Carrillo E, Schiappacassi M, Campos R

Abstract excerpt

Foot-and-mouth disease virus (FMDV) shows a remarkable antigenic variability and, like other RNA viruses, presents a high rate of mutation. It has been proposed that selection exerted by antibodies of the host could play a major role in the rapid evolution of FMDV. The present work reports the selection of FMDV antibody-resistant (Nr) populations after serial passages of a cloned FMDV O1 Caseros strain on...

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Identifiers

PMID: 1374806
DOI: 10.1128/JVI.66.6.3368-3372.1992
PMCID: PMC241116

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