Article
Genetic variation of foot-and-mouth disease virus from field outbreaks to laboratory isolation.
Virus research - 1 Jun 1994
Meyer R F, Pacciarini M, Hilyard E J, Ferrari S, Vakharia V N, Donini G, Brocchi E, Molitor T W
Abstract excerpt
Foot-and-mouth disease virus (FMDV), by nature of its RNA genome, possesses a high rate of mutation during replication. This results in extensive genetic polymorphism of virus populations in nature. The emergence of FMDV variants during replication has been reported. Genetic changes in the viral capsid protein (VP1) gene can result in amino acid changes affecting the immunodominant epitopes of FMDV. The genetic...
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