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Article

Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection

1 Oct 1993

Abstract excerpt

Antigenic variants of foot-and-mouth disease virus (FMDV) were generated and frequently became dominant in clonal populations of FMDV (clone C-S8c1) grown in the absence of anti-FMDV antibodies. We have now passaged eight samples of the same FMDV clone in the presence of a limited amount of neutralizing polyclonal antibodies directed to the major antigenic site A of capsid protein VP1. Complex populations of...

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Identifiers

PMID: 7690417
DOI: 10.1128/jvi.67.10.6071-6079.1993

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