Effects of L-ascorbic acid on the mutagenicity of ethyl methanesulfonate in cultured mammalian cells.

doi:10.1016/0027-5107(92)90175-2

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Article

Effects of L-ascorbic acid on the mutagenicity of ethyl methanesulfonate in cultured mammalian cells.

Mutation research - 1 Apr 1992

Kojima H, Konishi H, Kuroda Y

Abstract excerpt

The effects of L-ascorbic acid (AsA) on the mutations induced by ethyl methanesulfonate (EMS) were examined by means of the 6-thioguanine (6TG)-resistant mutation assay and chromosome aberration assay in cultured Chinese hamster V79 cells. When cells were treated with EMS at various concentration...

Topics

Animals
Ascorbic Acid
Cells, Cultured
Chromosome Aberrations
Cricetinae
Cricetulus
Ethyl Methanesulfonate
Mutation

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