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Article

FLT3 in lineage specification and plasticity.

Oncotarget - 1 May 2012

Greenblatt Sarah, Small Donald

Abstract excerpt

FLT3 is a receptor tyrosine kinase that is expressed in CD34+ hematopoietic stem/ progenitor cells (HSPCs) and is important for both normal myeloid and lymphoid differentiation. FLT3 expression in Pax5 negative lymphoid precursors coincides with a window of multilineage differentiation potential in mice and humans. Recent work has shown that FLT3 activating mutations can collaborate with a Nup98-HoxD13 mutation...

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Source

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Identifiers

PMID: 22643831
DOI: 10.18632/oncotarget.499
PMCID: PMC3388187

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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